Does the anti-virus program start as soon as I plug in my TegoStuff drive?

No, after you plug in your TegoStuff drive and the computer recognizes it, you can manually start the avti-virus program. If you connected your TegoStuff drive to a computer you feel is well protected and you are only going to use the TegoStuff drive for a short time, then you may skip starting the TegoStuff AV program.